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tarelli/nmlException.txt

Created February 13, 2016 13:29
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NML input String which generates the exception
Raw
nmlException.txt
<neuroml xmlns="http://www.neuroml.org/schema/neuroml2" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.neuroml.org/schema/neuroml2 https://raw.githubusercontent.com/NeuroML/NeuroML2/development/Schemas/NeuroML2/NeuroML_v2beta4.xsd" id="network_t3">
<notes>
Network structure (NeuroML 2beta4) for project: t3 saved with neuroConstruct v1.7.1 on: 19:48:05, 22-Oct-15
Cell Group: CG_C04_RS_sm contains 20 cells
Cell Group: CG_C04_AxAx_sm contains 10 cells
Cell Group: CG_C04_Bask_sm contains 10 cells
Cell Group: CG_C04_LTS_sm contains 10 cells
Cell Group: CG_C04_FRB_sm contains 6 cells
Network connection: RS_RS_gap_sm contains 24 individual synaptic connections
Network connection: AxAx_AxAx_gap_sm contains 20 individual synaptic connections
Network connection: LTS_AxAx_sm contains 200 individual synaptic connections
Network connection: Bask_FRB_sm contains 120 individual synaptic connections
Network connection: Bask_Bask_gap_sm contains 20 individual synaptic connections
Network connection: Bask_Bask_sm contains 200 individual synaptic connections
Network connection: Bask_RS_sm contains 400 individual synaptic connections
Network connection: LTS_RS_sm contains 1200 individual synaptic connections
Network connection: LTS_LTS_gap_sm contains 20 individual synaptic connections
Network connection: Bask_AxAx_sm contains 200 individual synaptic connections
Network connection: FRB_LTS_sm contains 100 individual synaptic connections
Network connection: AxAx_FRB_sm contains 120 individual synaptic connections
Network connection: RS_Bask_sm contains 900 individual synaptic connections
Net
work connection: FRB_RS_gap_sm contains 7 individual synaptic connections
Network connection: RS_AxAx_sm contains 900 individual synaptic connections
Network connection: FRB_Bask_sm contains 100 individual synaptic connections
Network connection: LTS_Pyr_sm contains 360 individual synaptic connections
Network connection: RS_LTS_sm contains 900 individual synaptic connections
Network connection: LTS_LTS_sm contains 200 individual synaptic connections
Network connection: Bask_LTS_sm contains 200 individual synaptic connections
Network connection: FRB_FRB_sm contains 30 individual synaptic connections
Network connection: RS_FRB_gap_sm contains 1 individual synaptic connections
Network connection: FRB_RS_sm contains 100 individual synaptic connections
Network connection: AxAx_RS_sm contains 400 individual synaptic connections
Network connection: LTS_Bask_sm contains 200 individual synaptic connections
Network connection: FRB_AxAx_sm contains 100 individual synaptic connections
Network connection: RS_FRB_sm contains 270 individual synaptic connections
Network connection: RS_RS_sm contains 900 individual synaptic connections
</notes>
<notes>ChannelML file based on Traub et al. 2003</notes>
<ionChannel id="cal" conductance="10pS" type="ionChannelHH" species="ca">
<notes>High threshold, long lasting Calcium L-type current. Based on NEURON port of FRB L2/3 model from Traub et al 2003. Same channel used in Traub et al 2005</notes>
<annotation>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
<rdf:Description rdf:about="cal">
<bqmodel:isDescribedBy xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
<rdf:Bag>
<rdf:li>Roger D. Traub, Eberhard H. Buhl, Tengis Gloveli, and Miles A. Whittington
Fast Rhythmic Bursting Can Be Induced in Layer 2/3 Cortical Neurons by Enhancing Persistent Na+ Conductance or by Blocking BK Channels
J Neurophysiol 89: 909-921, 2003</rdf:li>
<rdf:li rdf:resource="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=pubmed&amp;dopt=Abstract&amp;list_uids=12574468"/>
</rdf:Bag>
</bqmodel:isDescribedBy>
<bqmodel:isDescribedBy xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
<rdf:Bag>
<rdf:li>Roger D. Traub, Diego Contreras, Mark O. Cunningham, Hilary Murray, Fiona E. N. LeBeau, Anita Roopun, Andrea Bibbig, W. Bryan Wilent, Michael J. Higley, and Miles A. Whittington
Single-column thalamocortical network model exhibiting gamma oscillations, sleep spindles, and epileptogenic bursts.
J. Neurophysiol. 93, 2194-2232, 2005</rdf:li>
<rdf:li rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/15525801?dopt=Abstract"/>
</rdf:Bag>
</bqmodel:isDescribedBy>
<bqbiol:isVersionOf xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
<rdf:Bag>
<rdf:li>Calcium channels</rdf:li>
<rdf:li rdf:resource="http://senselab.med.yale.edu/senselab/NeuronDB/channelGene2.htm#table1"/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<gate id="m" type="gateHHrates" instances="2">
<forwardRate type="HHSigmoidRate" rate="1.6per_ms" scale="13.888889mV" midpoint="5mV"/>
<reverseRate type="HHExpLinearRate" rate="0.1per_ms" scale="-5mV" midpoint="-8.9mV"/>
</gate>
</ionChannel>
<notes>ChannelML file based on Traub et al. 2003</notes>
<ionChannel id="cat" conductance="10pS" type="ionChannelHH" species="cat">
<notes>Low threshold, inactivating Calcium T-type ("transient") conductance. Based on NEURON port of FRB L2/3 model from Traub et al 2003. Same channel used in Traub et al 2005</notes>
<annotation>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
<rdf:Description rdf:about="cat">
<bqmodel:isDescribedBy xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
<rdf:Bag>
<rdf:li>Roger D. Traub, Eberhard H. Buhl, Tengis Gloveli, and Miles A. Whittington
Fast Rhythmic Bursting Can Be Induced in Layer 2/3 Cortical Neurons by Enhancing Persistent Na+ Conductance or by Blocking BK Channels
J Neurophysiol 89: 909-921, 2003</rdf:li>
<rdf:li rdf:resource="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=pubmed&amp;dopt=Abstract&amp;list_uids=12574468"/>
</rdf:Bag>
</bqmodel:isDescribedBy>
<bqmodel:isDescribedBy xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
<rdf:Bag>
<rdf:li>Roger D. Traub, Diego Contreras, Mark O. Cunningham, Hilary Murray, Fiona E. N. LeBeau, Anita Roopun, Andrea Bibbig, W. Bryan Wilent, Michael J. Higley, and Miles A. Whittington
Single-column thalamocortical network model exhibiting gamma oscillations, sleep spindles, and epileptogenic bursts.
J. Neurophysiol. 93, 2194-2232, 2005</rdf:li>
<rdf:li rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/15525801?dopt=Abstract"/>
</rdf:Bag>
</bqmodel:isDescribedBy>
<bqbiol:isVersionOf xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
<rdf:Bag>
<rdf:li>Calcium channels</rdf:li>
<rdf:li rdf:resource="http://senselab.med.yale.edu/senselab/NeuronDB/channelGene2.htm#table1"/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<gate id="m" type="gateHHtauInf" instances="2">
<timeCourse type="cat_m_tau_tau"/>
<steadyState type="HHSigmoidVariable" rate="1" scale="6.2mV" midpoint="-56.0mV"/>
</gate>
<gate id="h" type="gateHHtauInf" instances="1">
<timeCourse type="cat_h_tau_tau"/>
<steadyState type="HHSigmoidVariable" rate="1" scale="-4mV" midpoint="-80mV"/>
</gate>
</ionChannel>
<ComponentType name="cat_m_tau_tau" extends="baseVoltageDepTime">
<Constant name="TIME_SCALE" dimension="time" value="1 ms"/>
<Constant name="VOLT_SCALE" dimension="voltage" value="1 mV"/>
<Dynamics>
<DerivedVariable name="V" dimension="none" value="v / VOLT_SCALE"/>
<DerivedVariable name="t" exposure="t" dimension="time" value="(0.204 + 0.333 / ( (exp ((15.8 + V) / 18.2 )) + (exp ((- V - 131) / 16.7)) )) * TIME_SCALE"/>
</Dynamics>
</ComponentType>
<ComponentType name="cat_h_tau_tau" extends="baseVoltageDepTime">
<Constant name="TIME_SCALE" dimension="time" value="1 ms"/>
<Constant name="VOLT_SCALE" dimension="voltage" value="1 mV"/>
<Dynamics>
<DerivedVariable name="V" dimension="none" value="v / VOLT_SCALE"/>
<ConditionalDerivedVariable name="t" exposure="t" dimension="time">
<Case condition="V .lt. ( -81.0 )" value="( 0.333 * (exp (( V + 466 ) / 66.6)) ) * TIME_SCALE"/>
<Case value="( 9.32 + 0.333 * (exp (( - V - 21 ) / 10.5))) * TIME_SCALE"/>
</ConditionalDerivedVariable>
</Dynamics>
</ComponentType>
<notes>ChannelML file based on Traub et al. 2003</notes>
<ionChannel id="cat_a" conductance="10pS" type="ionChannelHH" species="cat_a">
<notes>Low threshold, inactivating Calcium T-type ("transient") conductance. Based on Traub et al 2005, variation on CaT in Traub et al 2003</notes>
<annotation>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
<rdf:Description rdf:about="cat_a">
<bqmodel:isDescribedBy xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
<rdf:Bag>
<rdf:li>Roger D. Traub, Eberhard H. Buhl, Tengis Gloveli, and Miles A. Whittington
Fast Rhythmic Bursting Can Be Induced in Layer 2/3 Cortical Neurons by Enhancing Persistent Na+ Conductance or by Blocking BK Channels
J Neurophysiol 89: 909-921, 2003</rdf:li>
<rdf:li rdf:resource="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=pubmed&amp;dopt=Abstract&amp;list_uids=12574468"/>
</rdf:Bag>
</bqmodel:isDescribedBy>
<bqmodel:isDescribedBy xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
<rdf:Bag>
<rdf:li>Roger D. Traub, Diego Contreras, Mark O. Cunningham, Hilary Murray, Fiona E. N. LeBeau, Anita Roopun, Andrea Bibbig, W. Bryan Wilent, Michael J. Higley, and Miles A. Whittington
Single-column thalamocortical network model exhibiting gamma oscillations, sleep spindles, and epileptogenic bursts.
J. Neurophysiol. 93, 2194-2232, 2005</rdf:li>
<rdf:li rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/15525801?dopt=Abstract"/>
</rdf:Bag>
</bqmodel:isDescribedBy>
<bqbiol:isVersionOf xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
<rdf:Bag>
<rdf:li>Calcium channels</rdf:li>
<rdf:li rdf:resource="http://senselab.med.yale.edu/senselab/NeuronDB/channelGene2.htm#table1"/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<gate id="m" type="gateHHtauInf" instances="2">
<timeCourse type="cat_a_m_tau_tau"/>
<steadyState type="HHSigmoidVariable" rate="1" scale="7.4mV" midpoint="-52mV"/>
</gate>
<gate id="h" type="gateHHtauInf" instances="1">
<timeCourse type="cat_a_h_tau_tau"/>
<steadyState type="HHSigmoidVariable" rate="1" scale="-5mV" midpoint="-80mV"/>
</gate>
</ionChannel>
<ComponentType name="cat_a_m_tau_tau" extends="baseVoltageDepTime">
<Constant name="TIME_SCALE" dimension="time" value="1 ms"/>
<Constant name="VOLT_SCALE" dimension="voltage" value="1 mV"/>
<Dynamics>
<DerivedVariable name="V" dimension="none" value="v / VOLT_SCALE"/>
<DerivedVariable name="t" exposure="t" dimension="time" value="(1 + 0.33 / ( (exp ((V + 27) / 10 )) + (exp ((- V - 102) / 15)) )) * TIME_SCALE"/>
</Dynamics>
</ComponentType>
<ComponentType name="cat_a_h_tau_tau" extends="baseVoltageDepTime">
<Constant name="TIME_SCALE" dimension="time" value="1 ms"/>
<Constant name="VOLT_SCALE" dimension="voltage" value="1 mV"/>
<Dynamics>
<DerivedVariable name="V" dimension="none" value="v / VOLT_SCALE"/>
<DerivedVariable name="t" exposure="t" dimension="time" value="(28.3 + 0.33 / ((exp (( V + 48)/ 4)) + (exp ( ( -V - 407) / 50 )) ) ) * TIME_SCALE"/>
</Dynamics>
</ComponentType>
<notes>ChannelML file describing a single synaptic mechanism</notes>
<expTwoSynapse id="Exc_Pyr_Int" tauRise="0.8ms" tauDecay="0.8ms" gbase="0.88291065831095217E-6mS" erev="0mV">
<notes>Simple example of a synaptic mechanism, which consists of a postsynaptic conductance which changes as
double exponential function of time. Mappings exist for NEURON and GENESIS.</notes>
</expTwoSynapse>
<notes>ChannelML file describing a single synaptic mechanism</notes>
<expTwoSynapse id="Exc_Pyr_Pyr" tauRise="2ms" tauDecay="2ms" gbase="0.18393972e-6mS" erev="0mV">
<notes>Simple example of a synaptic mechanism, which consists of a postsynaptic conductance which changes as
double exponential function of time. Mappings exist for NEURON and GENESIS.</notes>
</expTwoSynapse>
<notes>ChannelML file describing a single synaptic mechanism</notes>
<gapJunction id="GapJuncCML" conductance="3E-6mS"/>
<notes>ChannelML file describing a single synaptic mechanism</notes>
<gapJunction id="GapJuncFS" conductance="1E-6mS"/>
<notes>ChannelML file describing a single synaptic mechanism</notes>
<gapJunction id="GapJuncLTS" conductance="1E-6mS"/>
<notes>ChannelML file describing a single synaptic mechanism</notes>
<expOneSynapse id="Inh_Axo_Pyr" tauDecay="6ms" gbase="0.4E-6mS" erev="-70mV">
<notes>Simple example of a synaptic mechanism, which consists of a postsynaptic conductance which changes as
double exponential function of time. Mappings exist for NEURON and GENESIS.</notes>
</expOneSynapse>
<notes>ChannelML file describing a single synaptic mechanism</notes>
<expOneSynapse id="Inh_Bask_FS" tauDecay="6ms" gbase="0.2E-6mS" erev="-70mV">
<notes>Simple example of a synaptic mechanism, which consists of a postsynaptic conductance which changes as
double exponential function of time. Mappings exist for NEURON and GENESIS.</notes>
</expOneSynapse>
<notes>ChannelML file describing a single synaptic mechanism</notes>
<expOneSynapse id="Inh_Bask_LTS" tauDecay="6ms" gbase="1.0E-6mS" erev="-70mV">
<notes>Simple example of a synaptic mechanism, which consists of a postsynaptic conductance which changes as
double exponential function of time. Mappings exist for NEURON and GENESIS.</notes>
</expOneSynapse>
<notes>ChannelML file describing a single synaptic mechanism</notes>
<expOneSynapse id="Inh_Bask_Pyr" tauDecay="6ms" gbase="0.4e-6mS" erev="-70mV">
<notes>Simple example of a synaptic mechanism, which consists of a postsynaptic conductance which changes as
double exponential function of time. Mappings exist for NEURON and GENESIS.</notes>
</expOneSynapse>
<notes>ChannelML file describing a single synaptic mechanism</notes>
<expOneSynapse id="Inh_LTS_FS" tauDecay="20ms" gbase="0.025E-6mS" erev="-70mV">
<notes>Simple example of a synaptic mechanism, which consists of a postsynaptic conductance which changes as
double exponential function of time. Mappings exist for NEURON and GENESIS.</notes>
</expOneSynapse>
<notes>ChannelML file describing a single synaptic mechanism</notes>
<expOneSynapse id="Inh_LTS_LTS" tauDecay="20ms" gbase="0.05E-6mS" erev="-70mV">
<notes>Simple example of a synaptic mechanism, which consists of a postsynaptic conductance which changes as
double exponential function of time. Mappings exist for NEURON and GENESIS.</notes>
</expOneSynapse>
<notes>ChannelML file describing a single synaptic mechanism</notes>
<expOneSynapse id="Inh_LTS_Pyr" tauDecay="20ms" gbase="0.2E-6mS" erev="-70mV">
<notes>Simple example of a synaptic mechanism, which consists of a postsynaptic conductance which changes as
double exponential function of time. Mappings exist for NEURON and GENESIS.</notes>
</expOneSynapse>
<notes>ChannelML file based on Traub et al. 2003</notes>
<ionChannel id="k2" conductance="10pS" type="ionChannelHH" species="k">
<notes>Potasium K2-type current (slowly activating and inactivating). Based on NEURON port of FRB L2/3 model from Traub et al 2003. Same channel used in Traub et al 2005</notes>
<annotation>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
<rdf:Description rdf:about="k2">
<bqmodel:isDescribedBy xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
<rdf:Bag>
<rdf:li>Roger D. Traub, Eberhard H. Buhl, Tengis Gloveli, and Miles A. Whittington
Fast Rhythmic Bursting Can Be Induced in Layer 2/3 Cortical Neurons by Enhancing Persistent Na+ Conductance or by Blocking BK Channels
J Neurophysiol 89: 909-921, 2003</rdf:li>
<rdf:li rdf:resource="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=pubmed&amp;dopt=Abstract&amp;list_uids=12574468"/>
</rdf:Bag>
</bqmodel:isDescribedBy>
<bqmodel:isDescribedBy xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
<rdf:Bag>
<rdf:li>Roger D. Traub, Diego Contreras, Mark O. Cunningham, Hilary Murray, Fiona E. N. LeBeau, Anita Roopun, Andrea Bibbig, W. Bryan Wilent, Michael J. Higley, and Miles A. Whittington
Single-column thalamocortical network model exhibiting gamma oscillations, sleep spindles, and epileptogenic bursts.
J. Neurophysiol. 93, 2194-2232, 2005</rdf:li>
<rdf:li rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/15525801?dopt=Abstract"/>
</rdf:Bag>
</bqmodel:isDescribedBy>
<bqbiol:isVersionOf xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
<rdf:Bag>
<rdf:li>K channels</rdf:li>
<rdf:li rdf:resource="http://senselab.med.yale.edu/senselab/NeuronDB/channelGene2.htm#table3"/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<gate id="m" type="gateHHtauInf" instances="1">
<timeCourse type="k2_m_tau_tau"/>
<steadyState type="HHSigmoidVariable" rate="1" scale="17mV" midpoint="-10mV"/>
</gate>
<gate id="h" type="gateHHtauInf" instances="1">
<timeCourse type="k2_h_tau_tau"/>
<steadyState type="HHSigmoidVariable" rate="1" scale="-10.6mV" midpoint="-58mV"/>
</gate>
</ionChannel>
<ComponentType name="k2_m_tau_tau" extends="baseVoltageDepTime">
<Constant name="TIME_SCALE" dimension="time" value="1 ms"/>
<Constant name="VOLT_SCALE" dimension="voltage" value="1 mV"/>
<Dynamics>
<DerivedVariable name="V" dimension="none" value="v / VOLT_SCALE"/>
<DerivedVariable name="t" exposure="t" dimension="time" value="(4.95 + 0.5 / ( (exp ( (V - 81) / 25.6)) + (exp ( (- V - 132) / 18 )))) * TIME_SCALE"/>
</Dynamics>
</ComponentType>
<ComponentType name="k2_h_tau_tau" extends="baseVoltageDepTime">
<Constant name="TIME_SCALE" dimension="time" value="1 ms"/>
<Constant name="VOLT_SCALE" dimension="voltage" value="1 mV"/>
<Dynamics>
<DerivedVariable name="V" dimension="none" value="v / VOLT_SCALE"/>
<DerivedVariable name="t" exposure="t" dimension="time" value="(60 + 0.5 / ((exp (( V - 1.33 )/200)) + (exp ((- V - 130)/ 7.1)))) * TIME_SCALE"/>
</Dynamics>
</ComponentType>
<notes>ChannelML file based on Traub et al. 2003</notes>
<ionChannel id="ka" conductance="10pS" type="ionChannelHH" species="k">
<notes>Potasium A-type conductance (transient, inactivating). Based on NEURON port of FRB L2/3 model from Traub et al 2003. Same channel used in Traub et al 2005</notes>
<annotation>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
<rdf:Description rdf:about="ka">
<bqmodel:isDescribedBy xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
<rdf:Bag>
<rdf:li>Roger D. Traub, Eberhard H. Buhl, Tengis Gloveli, and Miles A. Whittington
Fast Rhythmic Bursting Can Be Induced in Layer 2/3 Cortical Neurons by Enhancing Persistent Na+ Conductance or by Blocking BK Channels
J Neurophysiol 89: 909-921, 2003</rdf:li>
<rdf:li rdf:resource="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=pubmed&amp;dopt=Abstract&amp;list_uids=12574468"/>
</rdf:Bag>
</bqmodel:isDescribedBy>
<bqmodel:isDescribedBy xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
<rdf:Bag>
<rdf:li>Roger D. Traub, Diego Contreras, Mark O. Cunningham, Hilary Murray, Fiona E. N. LeBeau, Anita Roopun, Andrea Bibbig, W. Bryan Wilent, Michael J. Higley, and Miles A. Whittington
Single-column thalamocortical network model exhibiting gamma oscillations, sleep spindles, and epileptogenic bursts.
J. Neurophysiol. 93, 2194-2232, 2005</rdf:li>
<rdf:li rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/15525801?dopt=Abstract"/>
</rdf:Bag>
</bqmodel:isDescribedBy>
<bqbiol:isVersionOf xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
<rdf:Bag>
<rdf:li>K channels</rdf:li>
<rdf:li rdf:resource="http://senselab.med.yale.edu/senselab/NeuronDB/channelGene2.htm#table3"/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<gate id="m" type="gateHHtauInf" instances="4">
<timeCourse type="ka_m_tau_tau"/>
<steadyState type="HHSigmoidVariable" rate="1" scale="8.5mV" midpoint="-60mV"/>
</gate>
<gate id="h" type="gateHHtauInf" instances="1">
<timeCourse type="ka_h_tau_tau"/>
<steadyState type="HHSigmoidVariable" rate="1" scale="-6mV" midpoint="-78mV"/>
</gate>
</ionChannel>
<ComponentType name="ka_m_tau_tau" extends="baseVoltageDepTime">
<Constant name="TIME_SCALE" dimension="time" value="1 ms"/>
<Constant name="VOLT_SCALE" dimension="voltage" value="1 mV"/>
<Dynamics>
<DerivedVariable name="V" dimension="none" value="v / VOLT_SCALE"/>
<DerivedVariable name="t" exposure="t" dimension="time" value="(0.185 + 0.5 / ((exp (( V + 35.8 )/19.7)) + (exp ((-V - 79.7)/12.7)))) * TIME_SCALE"/>
</Dynamics>
</ComponentType>
<ComponentType name="ka_h_tau_tau" extends="baseVoltageDepTime">
<Constant name="TIME_SCALE" dimension="time" value="1 ms"/>
<Constant name="VOLT_SCALE" dimension="voltage" value="1 mV"/>
<Dynamics>
<DerivedVariable name="V" dimension="none" value="v / VOLT_SCALE"/>
<ConditionalDerivedVariable name="t" exposure="t" dimension="time">
<Case condition="V .lt. ( -63.0 )" value="( 0.5 / ((exp (( V + 46 )/5)) + (exp (( -V - 238 )/37.5))) ) * TIME_SCALE"/>
<Case value="( 9.5) * TIME_SCALE"/>
</ConditionalDerivedVariable>
</Dynamics>
</ComponentType>
<notes>ChannelML file based on Traub et al. 2003</notes>
<ionChannel id="kahp" conductance="10pS" type="ionChannelHH" species="k">
<notes>[Ca2+] dependent K AHP (afterhyperpolarization) conductance. Based on NEURON port of FRB L2/3 model from Traub et al 2003. Same channel used in Traub et al 2005</notes>
<annotation>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
<rdf:Description rdf:about="kahp">
<bqmodel:isDescribedBy xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
<rdf:Bag>
<rdf:li>Roger D. Traub, Eberhard H. Buhl, Tengis Gloveli, and Miles A. Whittington
Fast Rhythmic Bursting Can Be Induced in Layer 2/3 Cortical Neurons by Enhancing Persistent Na+ Conductance or by Blocking BK Channels
J Neurophysiol 89: 909-921, 2003</rdf:li>
<rdf:li rdf:resource="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=pubmed&amp;dopt=Abstract&amp;list_uids=12574468"/>
</rdf:Bag>
</bqmodel:isDescribedBy>
<bqmodel:isDescribedBy xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
<rdf:Bag>
<rdf:li>Roger D. Traub, Diego Contreras, Mark O. Cunningham, Hilary Murray, Fiona E. N. LeBeau, Anita Roopun, Andrea Bibbig, W. Bryan Wilent, Michael J. Higley, and Miles A. Whittington
Single-column thalamocortical network model exhibiting gamma oscillations, sleep spindles, and epileptogenic bursts.
J. Neurophysiol. 93, 2194-2232, 2005</rdf:li>
<rdf:li rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/15525801?dopt=Abstract"/>
</rdf:Bag>
</bqmodel:isDescribedBy>
<bqbiol:isVersionOf xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
<rdf:Bag>
<rdf:li>K channels</rdf:li>
<rdf:li rdf:resource="http://senselab.med.yale.edu/senselab/NeuronDB/channelGene2.htm#table3"/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<gate id="m" type="gateHHrates" instances="1">
<forwardRate type="kahp_m_alpha_rate"/>
<reverseRate type="kahp_m_beta_rate"/>
</gate>
</ionChannel>
<ComponentType name="kahp_m_alpha_rate" extends="baseVoltageConcDepRate">
<Constant name="TIME_SCALE" dimension="time" value="1 ms"/>
<Constant name="VOLT_SCALE" dimension="voltage" value="1 mV"/>
<Constant name="CONC_SCALE" dimension="concentration" value="1 mol_per_cm3"/>
<Dynamics>
<DerivedVariable name="V" dimension="none" value="v / VOLT_SCALE"/>
<DerivedVariable name="ca_conc" dimension="none" value="caConc / CONC_SCALE"/>
<ConditionalDerivedVariable name="r" exposure="r" dimension="per_time">
<Case condition="ca_conc .lt. ( 0.0001 )" value="( ca_conc/0.01 ) / TIME_SCALE"/>
<Case value="( 0.01) / TIME_SCALE"/>
</ConditionalDerivedVariable>
</Dynamics>
</ComponentType>
<ComponentType name="kahp_m_beta_rate" extends="baseVoltageConcDepRate">
<Constant name="TIME_SCALE" dimension="time" value="1 ms"/>
<Constant name="VOLT_SCALE" dimension="voltage" value="1 mV"/>
<Constant name="CONC_SCALE" dimension="concentration" value="1 mol_per_cm3"/>
<Dynamics>
<DerivedVariable name="V" dimension="none" value="v / VOLT_SCALE"/>
<DerivedVariable name="ca_conc" dimension="none" value="caConc / CONC_SCALE"/>
<DerivedVariable name="r" exposure="r" dimension="per_time" value="(0.01) / TIME_SCALE"/>
</Dynamics>
</ComponentType>
<notes>ChannelML file based on Traub et al. 2003</notes>
<ionChannel id="kahp_slower" conductance="10pS" type="ionChannelHH" species="k">
<notes>Slow [Ca2+] dependent K AHP (afterhyperpolarization) conductance. Slower version of kahp from Traub et al 2003</notes>
<annotation>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
<rdf:Description rdf:about="kahp_slower">
<bqmodel:isDescribedBy xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
<rdf:Bag>
<rdf:li>Roger D. Traub, Eberhard H. Buhl, Tengis Gloveli, and Miles A. Whittington
Fast Rhythmic Bursting Can Be Induced in Layer 2/3 Cortical Neurons by Enhancing Persistent Na+ Conductance or by Blocking BK Channels
J Neurophysiol 89: 909-921, 2003</rdf:li>
<rdf:li rdf:resource="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=pubmed&amp;dopt=Abstract&amp;list_uids=12574468"/>
</rdf:Bag>
</bqmodel:isDescribedBy>
<bqmodel:isDescribedBy xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
<rdf:Bag>
<rdf:li>Roger D. Traub, Diego Contreras, Mark O. Cunningham, Hilary Murray, Fiona E. N. LeBeau, Anita Roopun, Andrea Bibbig, W. Bryan Wilent, Michael J. Higley, and Miles A. Whittington
Single-column thalamocortical network model exhibiting gamma oscillations, sleep spindles, and epileptogenic bursts.
J. Neurophysiol. 93, 2194-2232, 2005</rdf:li>
<rdf:li rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/15525801?dopt=Abstract"/>
</rdf:Bag>
</bqmodel:isDescribedBy>
<bqbiol:isVersionOf xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
<rdf:Bag>
<rdf:li>K channels</rdf:li>
<rdf:li rdf:resource="http://senselab.med.yale.edu/senselab/NeuronDB/channelGene2.htm#table3"/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<gate id="m" type="gateHHrates" instances="1">
<forwardRate type="kahp_slower_m_alpha_rate"/>
<reverseRate type="kahp_slower_m_beta_rate"/>
</gate>
</ionChannel>
<ComponentType name="kahp_slower_m_alpha_rate" extends="baseVoltageConcDepRate">
<Constant name="TIME_SCALE" dimension="time" value="1 ms"/>
<Constant name="VOLT_SCALE" dimension="voltage" value="1 mV"/>
<Constant name="CONC_SCALE" dimension="concentration" value="1 mol_per_cm3"/>
<Dynamics>
<DerivedVariable name="V" dimension="none" value="v / VOLT_SCALE"/>
<DerivedVariable name="ca_conc" dimension="none" value="caConc / CONC_SCALE"/>
<ConditionalDerivedVariable name="r" exposure="r" dimension="per_time">
<Case condition="ca_conc .lt. ( 0.0005 )" value="( ca_conc/0.05 ) / TIME_SCALE"/>
<Case value="( 0.01) / TIME_SCALE"/>
</ConditionalDerivedVariable>
</Dynamics>
</ComponentType>
<ComponentType name="kahp_slower_m_beta_rate" extends="baseVoltageConcDepRate">
<Constant name="TIME_SCALE" dimension="time" value="1 ms"/>
<Constant name="VOLT_SCALE" dimension="voltage" value="1 mV"/>
<Constant name="CONC_SCALE" dimension="concentration" value="1 mol_per_cm3"/>
<Dynamics>
<DerivedVariable name="V" dimension="none" value="v / VOLT_SCALE"/>
<DerivedVariable name="ca_conc" dimension="none" value="caConc / CONC_SCALE"/>
<DerivedVariable name="r" exposure="r" dimension="per_time" value="(0.001) / TIME_SCALE"/>
</Dynamics>
</ComponentType>
<notes>ChannelML file based on Traub et al. 2003</notes>
<ionChannel id="kc" conductance="10pS" type="ionChannelHH" species="k">
<notes>Fast voltage and [Ca2+] dependent K conductance (BK channel). Based on NEURON port of FRB L2/3 model from Traub et al 2003. Same channel used in Traub et al 2005</notes>
<annotation>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
<rdf:Description rdf:about="kc">
<bqmodel:isDescribedBy xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
<rdf:Bag>
<rdf:li>Roger D. Traub, Eberhard H. Buhl, Tengis Gloveli, and Miles A. Whittington
Fast Rhythmic Bursting Can Be Induced in Layer 2/3 Cortical Neurons by Enhancing Persistent Na+ Conductance or by Blocking BK Channels
J Neurophysiol 89: 909-921, 2003</rdf:li>
<rdf:li rdf:resource="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=pubmed&amp;dopt=Abstract&amp;list_uids=12574468"/>
</rdf:Bag>
</bqmodel:isDescribedBy>
<bqmodel:isDescribedBy xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
<rdf:Bag>
<rdf:li>Roger D. Traub, Diego Contreras, Mark O. Cunningham, Hilary Murray, Fiona E. N. LeBeau, Anita Roopun, Andrea Bibbig, W. Bryan Wilent, Michael J. Higley, and Miles A. Whittington
Single-column thalamocortical network model exhibiting gamma oscillations, sleep spindles, and epileptogenic bursts.
J. Neurophysiol. 93, 2194-2232, 2005</rdf:li>
<rdf:li rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/15525801?dopt=Abstract"/>
</rdf:Bag>
</bqmodel:isDescribedBy>
<bqbiol:isVersionOf xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
<rdf:Bag>
<rdf:li>K channels</rdf:li>
<rdf:li rdf:resource="http://senselab.med.yale.edu/senselab/NeuronDB/channelGene2.htm#table3"/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<baseConductanceScalingCaDependent type="cond_scaling_kc"/>
<gate id="m" type="gateHHrates" instances="1">
<forwardRate type="kc_m_alpha_rate"/>
<reverseRate type="kc_m_beta_rate"/>
</gate>
</ionChannel>
<ComponentType name="cond_scaling_kc" extends="baseConductanceScalingCaDependent">
<Constant name="CONC_SCALE" dimension="concentration" value="1 mol_per_cm3"/>
<Dynamics>
<DerivedVariable name="ca_conc" dimension="none" value="caConc / CONC_SCALE"/>
<ConditionalDerivedVariable name="factor" exposure="factor" dimension="none">
<Case condition="ca_conc .lt. ( 0.00025 )" value=" (ca_conc / 0.00025) "/>
<Case value=" 1"/>
</ConditionalDerivedVariable>
</Dynamics>
</ComponentType>
<ComponentType name="kc_m_alpha_rate" extends="baseVoltageDepRate">
<Constant name="TIME_SCALE" dimension="time" value="1 ms"/>
<Constant name="VOLT_SCALE" dimension="voltage" value="1 mV"/>
<Dynamics>
<DerivedVariable name="V" dimension="none" value="v / VOLT_SCALE"/>
<ConditionalDerivedVariable name="r" exposure="r" dimension="per_time">
<Case condition="V .lt. ( -10 )" value="( (2 / 37.95) * ( exp ( ((V + 50 ) / 11) - (( V + 53.5) / 27) ) ) ) / TIME_SCALE"/>
<Case value="( 2 * (exp ( ( (-1 * V) - 53.5 ) / 27 ))) / TIME_SCALE"/>
</ConditionalDerivedVariable>
</Dynamics>
</ComponentType>
<ComponentType name="kc_m_beta_rate" extends="baseVoltageDepRate">
<Constant name="TIME_SCALE" dimension="time" value="1 ms"/>
<Constant name="VOLT_SCALE" dimension="voltage" value="1 mV"/>
<Requirement name="alpha" dimension="per_time"/>
<Requirement name="beta" dimension="per_time"/>
<Dynamics>
<DerivedVariable name="V" dimension="none" value="v / VOLT_SCALE"/>
<DerivedVariable name="ALPHA" dimension="none" value="alpha * TIME_SCALE"/>
<DerivedVariable name="BETA" dimension="none" value="beta * TIME_SCALE"/>
<ConditionalDerivedVariable name="r" exposure="r" dimension="per_time">
<Case condition="V .lt. ( -10 )" value="( 2 * (exp ( ( (-1 * V) - 53.5 ) / 27 )) - ALPHA ) / TIME_SCALE"/>
<Case value="( 0.0) / TIME_SCALE"/>
</ConditionalDerivedVariable>
</Dynamics>
</ComponentType>
<notes>ChannelML file based on Traub et al. 2003</notes>
<ionChannel id="kc_fast" conductance="10pS" type="ionChannelHH" species="k">
<notes>Fast voltage and [Ca2+] dependent K conductance (BK channel). Based on NEURON port of FRB L2/3 model from Traub et al 2003. Same channel used in Traub et al 2005</notes>
<annotation>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
<rdf:Description rdf:about="kc_fast">
<bqmodel:isDescribedBy xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
<rdf:Bag>
<rdf:li>Roger D. Traub, Eberhard H. Buhl, Tengis Gloveli, and Miles A. Whittington
Fast Rhythmic Bursting Can Be Induced in Layer 2/3 Cortical Neurons by Enhancing Persistent Na+ Conductance or by Blocking BK Channels
J Neurophysiol 89: 909-921, 2003</rdf:li>
<rdf:li rdf:resource="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=pubmed&amp;dopt=Abstract&amp;list_uids=12574468"/>
</rdf:Bag>
</bqmodel:isDescribedBy>
<bqmodel:isDescribedBy xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
<rdf:Bag>
<rdf:li>Roger D. Traub, Diego Contreras, Mark O. Cunningham, Hilary Murray, Fiona E. N. LeBeau, Anita Roopun, Andrea Bibbig, W. Bryan Wilent, Michael J. Higley, and Miles A. Whittington
Single-column thalamocortical network model exhibiting gamma oscillations, sleep spindles, and epileptogenic bursts.
J. Neurophysiol. 93, 2194-2232, 2005</rdf:li>
<rdf:li rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/15525801?dopt=Abstract"/>
</rdf:Bag>
</bqmodel:isDescribedBy>
<bqbiol:isVersionOf xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
<rdf:Bag>
<rdf:li>K channels</rdf:li>
<rdf:li rdf:resource="http://senselab.med.yale.edu/senselab/NeuronDB/channelGene2.htm#table3"/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<baseConductanceScalingCaDependent type="cond_scaling_kc_fast"/>
<gate id="m" type="gateHHrates" instances="1">
<forwardRate type="kc_fast_m_alpha_rate"/>
<reverseRate type="kc_fast_m_beta_rate"/>
</gate>
</ionChannel>
<ComponentType name="cond_scaling_kc_fast" extends="baseConductanceScalingCaDependent">
<Constant name="CONC_SCALE" dimension="concentration" value="1 mol_per_cm3"/>
<Dynamics>
<DerivedVariable name="ca_conc" dimension="none" value="caConc / CONC_SCALE"/>
<ConditionalDerivedVariable name="factor" exposure="factor" dimension="none">
<Case condition="ca_conc .lt. ( 0.00025 )" value=" (ca_conc / 0.00025) "/>
<Case value=" 1"/>
</ConditionalDerivedVariable>
</Dynamics>
</ComponentType>
<ComponentType name="kc_fast_m_alpha_rate" extends="baseVoltageDepRate">
<Constant name="TIME_SCALE" dimension="time" value="1 ms"/>
<Constant name="VOLT_SCALE" dimension="voltage" value="1 mV"/>
<Constant name="speedup_factor" dimension="none" value="2"/>
<Dynamics>
<DerivedVariable name="V" dimension="none" value="v / VOLT_SCALE"/>
<ConditionalDerivedVariable name="r" exposure="r" dimension="per_time">
<Case condition="V .lt. ( -10 )" value="( speedup_factor * (2 / 37.95) * ( exp ( ((V + 50 ) / 11) - (( V + 53.5) / 27) ) ) ) / TIME_SCALE"/>
<Case value="( speedup_factor * 2 * (exp ( ( (-1 * V) - 53.5 ) / 27 ))) / TIME_SCALE"/>
</ConditionalDerivedVariable>
</Dynamics>
</ComponentType>
<ComponentType name="kc_fast_m_beta_rate" extends="baseVoltageDepRate">
<Constant name="TIME_SCALE" dimension="time" value="1 ms"/>
<Constant name="VOLT_SCALE" dimension="voltage" value="1 mV"/>
<Constant name="speedup_factor" dimension="none" value="2"/>
<Requirement name="alpha" dimension="per_time"/>
<Requirement name="beta" dimension="per_time"/>
<Dynamics>
<DerivedVariable name="V" dimension="none" value="v / VOLT_SCALE"/>
<DerivedVariable name="ALPHA" dimension="none" value="alpha * TIME_SCALE"/>
<DerivedVariable name="BETA" dimension="none" value="beta * TIME_SCALE"/>
<ConditionalDerivedVariable name="r" exposure="r" dimension="per_time">
<Case condition="V .lt. ( -10 )" value="( speedup_factor * 2 * (exp ( ( (-1 * V) - 53.5 ) / 27 )) - ALPHA ) / TIME_SCALE"/>
<Case value="( speedup_factor * 0.0) / TIME_SCALE"/>
</ConditionalDerivedVariable>
</Dynamics>
</ComponentType>
<notes>ChannelML file based on Traub et al. 2003</notes>
<ionChannel id="kdr" conductance="10pS" type="ionChannelHH" species="k">
<notes>Delayed rectifier potassium conductance. Based on NEURON port of FRB L2/3 model from Traub et al 2003. Same channel used in Traub et al 2005</notes>
<annotation>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
<rdf:Description rdf:about="kdr">
<bqmodel:isDescribedBy xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
<rdf:Bag>
<rdf:li>Roger D. Traub, Eberhard H. Buhl, Tengis Gloveli, and Miles A. Whittington
Fast Rhythmic Bursting Can Be Induced in Layer 2/3 Cortical Neurons by Enhancing Persistent Na+ Conductance or by Blocking BK Channels
J Neurophysiol 89: 909-921, 2003</rdf:li>
<rdf:li rdf:resource="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=pubmed&amp;dopt=Abstract&amp;list_uids=12574468"/>
</rdf:Bag>
</bqmodel:isDescribedBy>
<bqmodel:isDescribedBy xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
<rdf:Bag>
<rdf:li>Roger D. Traub, Diego Contreras, Mark O. Cunningham, Hilary Murray, Fiona E. N. LeBeau, Anita Roopun, Andrea Bibbig, W. Bryan Wilent, Michael J. Higley, and Miles A. Whittington
Single-column thalamocortical network model exhibiting gamma oscillations, sleep spindles, and epileptogenic bursts.
J. Neurophysiol. 93, 2194-2232, 2005</rdf:li>
<rdf:li rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/15525801?dopt=Abstract"/>
</rdf:Bag>
</bqmodel:isDescribedBy>
<bqbiol:isVersionOf xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
<rdf:Bag>
<rdf:li>K channels</rdf:li>
<rdf:li rdf:resource="http://senselab.med.yale.edu/senselab/NeuronDB/channelGene2.htm#table3"/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<gate id="m" type="gateHHtauInf" instances="4">
<timeCourse type="kdr_m_tau_tau"/>
<steadyState type="HHSigmoidVariable" rate="1" scale="10mV" midpoint="-29.5mV"/>
</gate>
</ionChannel>
<ComponentType name="kdr_m_tau_tau" extends="baseVoltageDepTime">
<Constant name="TIME_SCALE" dimension="time" value="1 ms"/>
<Constant name="VOLT_SCALE" dimension="voltage" value="1 mV"/>
<Dynamics>
<DerivedVariable name="V" dimension="none" value="v / VOLT_SCALE"/>
<ConditionalDerivedVariable name="t" exposure="t" dimension="time">
<Case condition="V .lt. ( -10 )" value="( 0.25 + 4.35 * (exp (( V + 10 )/10)) ) * TIME_SCALE"/>
<Case value="( 0.25 + 4.35 * (exp ((- V - 10)/ 10))) * TIME_SCALE"/>
</ConditionalDerivedVariable>
</Dynamics>
</ComponentType>
<notes>ChannelML file based on Traub et al. 2003</notes>
<ionChannel id="kdr_fs" conductance="10pS" type="ionChannelHH" species="k">
<notes>Potasium delayed rectifier type conductance for fast-spiking (FS) interneurons for RD Traub et al 2005</notes>
<annotation>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
<rdf:Description rdf:about="kdr_fs">
<bqmodel:isDescribedBy xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
<rdf:Bag>
<rdf:li>Roger D. Traub, Eberhard H. Buhl, Tengis Gloveli, and Miles A. Whittington
Fast Rhythmic Bursting Can Be Induced in Layer 2/3 Cortical Neurons by Enhancing Persistent Na+ Conductance or by Blocking BK Channels
J Neurophysiol 89: 909-921, 2003</rdf:li>
<rdf:li rdf:resource="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=pubmed&amp;dopt=Abstract&amp;list_uids=12574468"/>
</rdf:Bag>
</bqmodel:isDescribedBy>
<bqmodel:isDescribedBy xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
<rdf:Bag>
<rdf:li>Roger D. Traub, Diego Contreras, Mark O. Cunningham, Hilary Murray, Fiona E. N. LeBeau, Anita Roopun, Andrea Bibbig, W. Bryan Wilent, Michael J. Higley, and Miles A. Whittington
Single-column thalamocortical network model exhibiting gamma oscillations, sleep spindles, and epileptogenic bursts.
J. Neurophysiol. 93, 2194-2232, 2005</rdf:li>
<rdf:li rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/15525801?dopt=Abstract"/>
</rdf:Bag>
</bqmodel:isDescribedBy>
<bqbiol:isVersionOf xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
<rdf:Bag>
<rdf:li>K channels</rdf:li>
<rdf:li rdf:resource="http://senselab.med.yale.edu/senselab/NeuronDB/channelGene2.htm#table3"/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<gate id="m" type="gateHHtauInf" instances="4">
<timeCourse type="kdr_fs_m_tau_tau"/>
<steadyState type="HHSigmoidVariable" rate="1" scale="11.5mV" midpoint="-27mV"/>
</gate>
</ionChannel>
<ComponentType name="kdr_fs_m_tau_tau" extends="baseVoltageDepTime">
<Constant name="TIME_SCALE" dimension="time" value="1 ms"/>
<Constant name="VOLT_SCALE" dimension="voltage" value="1 mV"/>
<Dynamics>
<DerivedVariable name="V" dimension="none" value="v / VOLT_SCALE"/>
<ConditionalDerivedVariable name="t" exposure="t" dimension="time">
<Case condition="V .leq. ( -10 )" value="( 0.25 + 4.35 * (exp (( V + 10 )/10)) ) * TIME_SCALE"/>
<Case value="( 0.25 + 4.35 * (exp ((- V - 10)/ 10))) * TIME_SCALE"/>
</ConditionalDerivedVariable>
</Dynamics>
</ComponentType>
<notes>ChannelML file based on Traub et al. 2003</notes>
<ionChannel id="km" conductance="10pS" type="ionChannelHH" species="k">
<notes>Potasium M type current (muscarinic receptor-suppressed). Based on NEURON port of model from Traub et al 2003</notes>
<annotation>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
<rdf:Description rdf:about="km">
<bqmodel:isDescribedBy xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
<rdf:Bag>
<rdf:li>Roger D. Traub, Eberhard H. Buhl, Tengis Gloveli, and Miles A. Whittington
Fast Rhythmic Bursting Can Be Induced in Layer 2/3 Cortical Neurons by Enhancing Persistent Na+ Conductance or by Blocking BK Channels
J Neurophysiol 89: 909-921, 2003</rdf:li>
<rdf:li rdf:resource="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=pubmed&amp;dopt=Abstract&amp;list_uids=12574468"/>
</rdf:Bag>
</bqmodel:isDescribedBy>
<bqmodel:isDescribedBy xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
<rdf:Bag>
<rdf:li>Roger D. Traub, Diego Contreras, Mark O. Cunningham, Hilary Murray, Fiona E. N. LeBeau, Anita Roopun, Andrea Bibbig, W. Bryan Wilent, Michael J. Higley, and Miles A. Whittington
Single-column thalamocortical network model exhibiting gamma oscillations, sleep spindles, and epileptogenic bursts.
J. Neurophysiol. 93, 2194-2232, 2005</rdf:li>
<rdf:li rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/15525801?dopt=Abstract"/>
</rdf:Bag>
</bqmodel:isDescribedBy>
<bqbiol:isVersionOf xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
<rdf:Bag>
<rdf:li>K channels</rdf:li>
<rdf:li rdf:resource="http://senselab.med.yale.edu/senselab/NeuronDB/channelGene2.htm#table3"/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<gate id="m" type="gateHHrates" instances="1">
<forwardRate type="HHSigmoidRate" rate="0.02per_ms" scale="5mV" midpoint="-20mV"/>
<reverseRate type="HHExpRate" rate="0.01per_ms" scale="-18mV" midpoint="-43mV"/>
</gate>
</ionChannel>
<notes>ChannelML file based on Traub et al. 2003</notes>
<ionChannel id="ar__m00_25" conductance="10pS" type="ionChannelHH" species="ar">
<notes>Anomalous Rectifier conductance, also known as h-conductance (hyperpolarizing). Based on NEURON port of FRB L2/3 model from Traub et al 2003. Same channel used in Traub et al 2005</notes>
<annotation>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
<rdf:Description rdf:about="ar">
<bqmodel:isDescribedBy xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
<rdf:Bag>
<rdf:li>Roger D. Traub, Eberhard H. Buhl, Tengis Gloveli, and Miles A. Whittington
Fast Rhythmic Bursting Can Be Induced in Layer 2/3 Cortical Neurons by Enhancing Persistent Na+ Conductance or by Blocking BK Channels
J Neurophysiol 89: 909-921, 2003</rdf:li>
<rdf:li rdf:resource="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=pubmed&amp;dopt=Abstract&amp;list_uids=12574468"/>
</rdf:Bag>
</bqmodel:isDescribedBy>
<bqmodel:isDescribedBy xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
<rdf:Bag>
<rdf:li>Roger D. Traub, Diego Contreras, Mark O. Cunningham, Hilary Murray, Fiona E. N. LeBeau, Anita Roopun, Andrea Bibbig, W. Bryan Wilent, Michael J. Higley, and Miles A. Whittington
Single-column thalamocortical network model exhibiting gamma oscillations, sleep spindles, and epileptogenic bursts.
J. Neurophysiol. 93, 2194-2232, 2005</rdf:li>
<rdf:li rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/15525801?dopt=Abstract"/>
</rdf:Bag>
</bqmodel:isDescribedBy>
</rdf:Description>
</rdf:RDF>
</annotation>
<gate id="m" type="gateHHtauInf" instances="1">
<timeCourse type="ar__m00_25_m_tau_tau"/>
<steadyState type="HHSigmoidVariable" rate="1" scale="-5.5mV" midpoint="-75mV"/>
</gate>
</ionChannel>
<ComponentType name="ar__m00_25_m_tau_tau" extends="baseVoltageDepTime">
<Constant name="TIME_SCALE" dimension="time" value="1 ms"/>
<Constant name="VOLT_SCALE" dimension="voltage" value="1 mV"/>
<Constant name="m0" dimension="none" value="0.25"/>
<Dynamics>
<DerivedVariable name="V" dimension="none" value="v / VOLT_SCALE"/>
<DerivedVariable name="t" exposure="t" dimension="time" value="(1 /((exp (-14.6 - (0.086 * V) )) + (exp (-1.87 + (0.07 * V))))) * TIME_SCALE"/>
</Dynamics>
</ComponentType>
<notes>ChannelML file based on Traub et al. 2003</notes>
<fixedFactorConcentrationModelTraub id="cad__beta0_01__phi26000" restingConc="0mol_per_cm3" beta="0.01 per_ms" ion="ca" phi="26000.0 mol_per_cm_per_uA_per_ms"/>
<notes>ChannelML file based on Traub et al. 2003</notes>
<fixedFactorConcentrationModelTraub id="cad__beta0_05__phi52000" restingConc="0mol_per_cm3" beta="0.05 per_ms" ion="ca" phi="52000.0 mol_per_cm_per_uA_per_ms"/>
<notes>ChannelML file based on Traub et al. 2003</notes>
<ionChannel id="naf__a0__b0__c0__d0__fastNa_shiftmin3_5" conductance="10pS" type="ionChannelHH" species="na">
<notes>Fast Sodium transient (inactivating) current. Based on NEURON port of FRB L2/3 model from Traub et al 2003. Same channel used in Traub et al 2005</notes>
<annotation>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
<rdf:Description rdf:about="naf">
<bqmodel:isDescribedBy xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
<rdf:Bag>
<rdf:li>Roger D. Traub, Eberhard H. Buhl, Tengis Gloveli, and Miles A. Whittington
Fast Rhythmic Bursting Can Be Induced in Layer 2/3 Cortical Neurons by Enhancing Persistent Na+ Conductance or by Blocking BK Channels
J Neurophysiol 89: 909-921, 2003</rdf:li>
<rdf:li rdf:resource="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=pubmed&amp;dopt=Abstract&amp;list_uids=12574468"/>
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</bqmodel:isDescribedBy>
<bqmodel:isDescribedBy xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
<rdf:Bag>
<rdf:li>Roger D. Traub, Diego Contreras, Mark O. Cunningham, Hilary Murray, Fiona E. N. LeBeau, Anita Roopun, Andrea Bibbig, W. Bryan Wilent, Michael J. Higley, and Miles A. Whittington
Single-column thalamocortical network model exhibiting gamma oscillations, sleep spindles, and epileptogenic bursts.
J. Neurophysiol. 93, 2194-2232, 2005</rdf:li>
<rdf:li rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/15525801?dopt=Abstract"/>
</rdf:Bag>
</bqmodel:isDescribedBy>
<bqbiol:isVersionOf xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
<rdf:Bag>
<rdf:li>Na channels</rdf:li>
<rdf:li rdf:resource="http://senselab.med.yale.edu/senselab/NeuronDB/channelGene2.htm#table2"/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<gate id="m" type="gateHHtauInf" instances="3">
<timeCourse type="naf__a0__b0__c0__d0__fastNa_shiftmin3_5__a0__b0__c0__d0__fastNa_shiftmin3_5__a0__b0__c0__d0__fastNa_shiftmin3_5__a0__b0__c0__d0__fastNa_shiftmin3_5__a0__b0__c0__d0__fastNa_shiftmin3_5_m_tau_tau"/>
<steadyState type="naf__a0__b0__c0__d0__fastNa_shiftmin3_5__a0__b0__c0__d0__fastNa_shiftmin3_5__a0__b0__c0__d0__fastNa_shiftmin3_5__a0__b0__c0__d0__fastNa_shiftmin3_5__a0__b0__c0__d0__fastNa_shiftmin3_5_m_inf_inf"/>
</gate>
<gate id="h" type="gateHHtauInf" instances="1">
<timeCourse type="naf__a0__b0__c0__d0__fastNa_shiftmin3_5__a0__b0__c0__d0__fastNa_shiftmin3_5__a0__b0__c0__d0__fastNa_shiftmin3_5__a0__b0__c0__d0__fastNa_shiftmin3_5__a0__b0__c0__d0__fastNa_shiftmin3_5_h_tau_tau"/>
<steadyState type="naf__a0__b0__c0__d0__fastNa_shiftmin3_5__a0__b0__c0__d0__fastNa_shiftmin3_5__a0__b0__c0__d0__fastNa_shiftmin3_5__a0__b0__c0__d0__fastNa_shiftmin3_5__a0__b0__c0__d0__fastNa_shiftmin3_5_h_inf_inf"/>
</gate>
</ionChannel>
<ComponentType name="naf__a0__b0__c0__d0__fastNa_shiftmin3_5__a0__b0__c0__d0__fastNa_shiftmin3_5__a0__b0__c0__d0__fastNa_shiftmin3_5__a0__b0__c0__d0__fastNa_shiftmin3_5__a0__b0__c0__d0__fastNa_shiftmin3_5_m_tau_tau" extends="baseVoltageDepTime">
<Constant name="TIME_SCALE" dimension="time" value="1 ms"/>
<Constant name="VOLT_SCALE" dimension="voltage" value="1 mV"/>
<Constant name="fastNa_shift" dimension="none" value="-3.5"/>
<Constant name="a" dimension="none" value="0.0"/>
<Constant name="b" dimension="none" value="0.0"/>
<Constant name="c" dimension="none" value="0.0"/>
<Constant name="d" dimension="none" value="0.0"/>
<Dynamics>
<DerivedVariable name="V" dimension="none" value="v / VOLT_SCALE"/>
<ConditionalDerivedVariable name="t" exposure="t" dimension="time">
<Case condition="(V + fastNa_shift) .lt. ( -30 )" value="( 0.025 + 0.14 * ( exp ( ((V + fastNa_shift) + 30) / 10) ) ) * TIME_SCALE"/>
<Case value="( 0.02 + a + (0.145 + b) * ( exp ( -1 * ((V + fastNa_shift + d) + 30) / (10.0 + c)) )) * TIME_SCALE"/>
</ConditionalDerivedVariable>
</Dynamics>
</ComponentType>
<ComponentType name="naf__a0__b0__c0__d0__fastNa_shiftmin3_5__a0__b0__c0__d0__fastNa_shiftmin3_5__a0__b0__c0__d0__fastNa_shiftmin3_5__a0__b0__c0__d0__fastNa_shiftmin3_5__a0__b0__c0__d0__fastNa_shiftmin3_5_m_inf_inf" extends="baseVoltageDepVariable">
<Constant name="TIME_SCALE" dimension="time" value="1 ms"/>
<Constant name="VOLT_SCALE" dimension="voltage" value="1 mV"/>
<Constant name="fastNa_shift" dimension="none" value="-3.5"/>
<Constant name="a" dimension="none" value="0.0"/>
<Constant name="b" dimension="none" value="0.0"/>
<Constant name="c" dimension="none" value="0.0"/>
<Constant name="d" dimension="none" value="0.0"/>
<Dynamics>
<DerivedVariable name="V" dimension="none" value="v / VOLT_SCALE"/>
<DerivedVariable name="x" exposure="x" dimension="none" value=" 1 / ( 1 + (exp ( ( -1 * (V + fastNa_shift) - 38) / 10)) ) "/>
</Dynamics>
</ComponentType>
<ComponentType name="naf__a0__b0__c0__d0__fastNa_shiftmin3_5__a0__b0__c0__d0__fastNa_shiftmin3_5__a0__b0__c0__d0__fastNa_shiftmin3_5__a0__b0__c0__d0__fastNa_shiftmin3_5__a0__b0__c0__d0__fastNa_shiftmin3_5_h_tau_tau" extends="baseVoltageDepTime">
<Constant name="TIME_SCALE" dimension="time" value="1 ms"/>
<Constant name="VOLT_SCALE" dimension="voltage" value="1 mV"/>
<Constant name="fastNa_shift" dimension="none" value="-3.5"/>
<Constant name="a" dimension="none" value="0.0"/>
<Constant name="b" dimension="none" value="0.0"/>
<Constant name="c" dimension="none" value="0.0"/>
<Constant name="d" dimension="none" value="0.0"/>
<Dynamics>
<DerivedVariable name="V" dimension="none" value="v / VOLT_SCALE"/>
<DerivedVariable name="t" exposure="t" dimension="time" value="(0.15 + 1.15 / ( 1 + ( exp (( ( V + fastNa_shift * 0 ) + 37 ) / 15) ) )) * TIME_SCALE"/>
</Dynamics>
</ComponentType>
<ComponentType name="naf__a0__b0__c0__d0__fastNa_shiftmin3_5__a0__b0__c0__d0__fastNa_shiftmin3_5__a0__b0__c0__d0__fastNa_shiftmin3_5__a0__b0__c0__d0__fastNa_shiftmin3_5__a0__b0__c0__d0__fastNa_shiftmin3_5_h_inf_inf" extends="baseVoltageDepVariable">
<Constant name="TIME_SCALE" dimension="time" value="1 ms"/>
<Constant name="VOLT_SCALE" dimension="voltage" value="1 mV"/>
<Constant name="fastNa_shift" dimension="none" value="-3.5"/>
<Constant name="a" dimension="none" value="0.0"/>
<Constant name="b" dimension="none" value="0.0"/>
<Constant name="c" dimension="none" value="0.0"/>
<Constant name="d" dimension="none" value="0.0"/>
<Dynamics>
<DerivedVariable name="V" dimension="none" value="v / VOLT_SCALE"/>
<DerivedVariable name="x" exposure="x" dimension="none" value="1 / ( 1 + (exp (( ( V + fastNa_shift * 0 ) + 62.9 ) / 10.7)) )"/>
</Dynamics>
</ComponentType>
<notes>ChannelML file based on Traub et al. 2003</notes>
<ionChannel id="nap" conductance="10pS" type="ionChannelHH" species="na">
<notes>Persistent (non inactivating) Sodium channel. Based on NEURON port of FRB L2/3 model from Traub et al 2003. Same channel used in Traub et al 2005</notes>
<annotation>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
<rdf:Description rdf:about="nap">
<bqmodel:isDescribedBy xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
<rdf:Bag>
<rdf:li>Roger D. Traub, Eberhard H. Buhl, Tengis Gloveli, and Miles A. Whittington
Fast Rhythmic Bursting Can Be Induced in Layer 2/3 Cortical Neurons by Enhancing Persistent Na+ Conductance or by Blocking BK Channels
J Neurophysiol 89: 909-921, 2003</rdf:li>
<rdf:li rdf:resource="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=pubmed&amp;dopt=Abstract&amp;list_uids=12574468"/>
</rdf:Bag>
</bqmodel:isDescribedBy>
<bqmodel:isDescribedBy xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
<rdf:Bag>
<rdf:li>Roger D. Traub, Diego Contreras, Mark O. Cunningham, Hilary Murray, Fiona E. N. LeBeau, Anita Roopun, Andrea Bibbig, W. Bryan Wilent, Michael J. Higley, and Miles A. Whittington
Single-column thalamocortical network model exhibiting gamma oscillations, sleep spindles, and epileptogenic bursts.
J. Neurophysiol. 93, 2194-2232, 2005</rdf:li>
<rdf:li rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/15525801?dopt=Abstract"/>
</rdf:Bag>
</bqmodel:isDescribedBy>
<bqbiol:isVersionOf xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
<rdf:Bag>
<rdf:li>Na channels</rdf:li>
<rdf:li rdf:resource="http://senselab.med.yale.edu/senselab/NeuronDB/channelGene2.htm#table2"/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<gate id="m" type="gateHHtauInf" instances="1">
<timeCourse type="nap_m_tau_tau"/>
<steadyState type="HHSigmoidVariable" rate="1" scale="10mV" midpoint="-48mV"/>
</gate>
</ionChannel>
<ComponentType name="nap_m_tau_tau" extends="baseVoltageDepTime">
<Constant name="TIME_SCALE" dimension="time" value="1 ms"/>
<Constant name="VOLT_SCALE" dimension="voltage" value="1 mV"/>
<Dynamics>
<DerivedVariable name="V" dimension="none" value="v / VOLT_SCALE"/>
<ConditionalDerivedVariable name="t" exposure="t" dimension="time">
<Case condition="V .lt. ( -40 )" value="( 0.025 + 0.14 * (exp (( V + 40 )/10)) ) * TIME_SCALE"/>
<Case value="( 0.02 + 0.145 * (exp (-1 * (V + 40)/ 10))) * TIME_SCALE"/>
</ConditionalDerivedVariable>
</Dynamics>
</ComponentType>
<notes>ChannelML file containing a single Channel description</notes>
<ionChannel id="pas" conductance="10pS" type="ionChannelPassive">
<notes>Simple passive leak conductance</notes>
</ionChannel>
<cell id="L23PyrFRB_varInit">
<notes>Cell: suppyrFRB_0 exported from NEURON ModelView
NOTE: This is a variant of L23PyrFRB which has a variable initial potential. This is used in the network model to initialise the FRB cells at different voltages, and so ensure they fire out of synchrony</notes>
<morphology id="morphology_L23PyrFRB_varInit">
<segment id="0" name="Seg0_comp_1">
<proximal x="0.0" y="0.0" z="0.0" diameter="16.0"/>
<distal x="0.0" y="7.5" z="0.0" diameter="16.0"/>
</segment>
<segment id="1" name="Seg1_comp_1">
<parent segment="0"/>
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</segment>
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<parent segment="0" fractionAlong="0.0"/>
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</segment>
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<parent segment="136"/>
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</segment>
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</segment>
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<biophysicalProperties id="biophys">
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<channelDensity condDensity="250.0 mS_per_cm2" id="naf_OneSecGrp_SectionRef_3" ionChannel="naf__a0__b0__c0__d0__fastNa_shiftmin3_5" segmentGroup="OneSecGrp_SectionRef_3" ion="na" erev="50.0 mV"/>
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<channelDensity condDensity="400.0 mS_per_cm2" id="naf_ModelViewParmSubset_2" ionChannel="naf__a0__b0__c0__d0__fastNa_shiftmin3_5" segmentGroup="ModelViewParmSubset_2" ion="na" erev="50.0 mV"/>
<channelDensity condDensity="0.48 mS_per_cm2" id="nap_ModelViewParmSubset_8" ionChannel="nap" segmentGroup="ModelViewParmSubset_8" ion="na" erev="50.0 mV"/>
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<channelDensity condDensity="0.64 mS_per_cm2" id="nap_OneSecGrp_SectionRef_3" ionChannel="nap" segmentGroup="OneSecGrp_SectionRef_3" ion="na" erev="50.0 mV"/>
<channelDensity condDensity="1.0 mS_per_cm2" id="pas_ModelViewParmSubset_2" ionChannel="pas" segmentGroup="ModelViewParmSubset_2" erev="-70.0 mV" ion="non_specific"/>
<channelDensity condDensity="0.02 mS_per_cm2" id="pas_OneSecGrp_SectionRef_1" ionChannel="pas" segmentGroup="OneSecGrp_SectionRef_1" erev="-70.0 mV" ion="non_specific"/>
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<spikeThresh value="0.0 mV"/>
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<initMembPotential value="-70.0 mV"/>
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<intracellularProperties>
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<species segmentGroup="OneSecGrp_SectionRef_1" id="ca" ion="ca" concentrationModel="cad__beta0_01__phi26000" initialConcentration="1.0E-8 mol_per_cm3" initialExtConcentration="2.0E-6 mol_per_cm3"/>
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</biophysicalProperties>
</cell>
<cell id="L23PyrRS">
<notes>Cell: suppyrRS_0 exported from NEURON ModelView</notes>
<morphology id="morphology_L23PyrRS">
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<channelDensity condDensity="0.12 mS_per_cm2" id="nap_ModelViewParmSubset_8" ionChannel="nap" segmentGroup="ModelViewParmSubset_8" ion="na" erev="50.0 mV"/>
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<spikeThresh value="0.0 mV"/>
<specificCapacitance segmentGroup="ModelViewParmSubset_4" value="1.8 uF_per_cm2"/>
<specificCapacitance segmentGroup="ModelViewParmSubset_3" value="0.9 uF_per_cm2"/>
<initMembPotential value="-70.0 mV"/>
</membraneProperties>
<intracellularProperties>
<species segmentGroup="ModelViewParmSubset_4" id="ca" ion="ca" concentrationModel="cad__beta0_05__phi52000" initialConcentration="1.0E-8 mol_per_cm3" initialExtConcentration="2.0E-6 mol_per_cm3"/>
<species segmentGroup="OneSecGrp_SectionRef_1" id="ca" ion="ca" concentrationModel="cad__beta0_01__phi26000" initialConcentration="1.0E-8 mol_per_cm3" initialExtConcentration="2.0E-6 mol_per_cm3"/>
<resistivity segmentGroup="ModelViewParmSubset_2" value="0.1 kohm_cm"/>
<resistivity segmentGroup="ModelViewParmSubset_1" value="0.25 kohm_cm"/>
</intracellularProperties>
</biophysicalProperties>
</cell>
<notes>ChannelML file based on Traub et al. 2003</notes>
<ionChannel id="naf" conductance="10pS" type="ionChannelHH" species="na">
<notes>Fast Sodium transient (inactivating) current. Based on NEURON port of FRB L2/3 model from Traub et al 2003. Same channel used in Traub et al 2005</notes>
<annotation>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
<rdf:Description rdf:about="naf">
<bqmodel:isDescribedBy xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
<rdf:Bag>
<rdf:li>Roger D. Traub, Eberhard H. Buhl, Tengis Gloveli, and Miles A. Whittington
Fast Rhythmic Bursting Can Be Induced in Layer 2/3 Cortical Neurons by Enhancing Persistent Na+ Conductance or by Blocking BK Channels
J Neurophysiol 89: 909-921, 2003</rdf:li>
<rdf:li rdf:resource="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=pubmed&amp;dopt=Abstract&amp;list_uids=12574468"/>
</rdf:Bag>
</bqmodel:isDescribedBy>
<bqmodel:isDescribedBy xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
<rdf:Bag>
<rdf:li>Roger D. Traub, Diego Contreras, Mark O. Cunningham, Hilary Murray, Fiona E. N. LeBeau, Anita Roopun, Andrea Bibbig, W. Bryan Wilent, Michael J. Higley, and Miles A. Whittington
Single-column thalamocortical network model exhibiting gamma oscillations, sleep spindles, and epileptogenic bursts.
J. Neurophysiol. 93, 2194-2232, 2005</rdf:li>
<rdf:li rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/15525801?dopt=Abstract"/>
</rdf:Bag>
</bqmodel:isDescribedBy>
<bqbiol:isVersionOf xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
<rdf:Bag>
<rdf:li>Na channels</rdf:li>
<rdf:li rdf:resource="http://senselab.med.yale.edu/senselab/NeuronDB/channelGene2.htm#table2"/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<gate id="m" type="gateHHtauInf" instances="3">
<timeCourse type="naf_m_tau_tau"/>
<steadyState type="naf_m_inf_inf"/>
</gate>
<gate id="h" type="gateHHtauInf" instances="1">
<timeCourse type="naf_h_tau_tau"/>
<steadyState type="naf_h_inf_inf"/>
</gate>
</ionChannel>
<ComponentType name="naf_m_tau_tau" extends="baseVoltageDepTime">
<Constant name="TIME_SCALE" dimension="time" value="1 ms"/>
<Constant name="VOLT_SCALE" dimension="voltage" value="1 mV"/>
<Constant name="fastNa_shift" dimension="none" value="0"/>
<Constant name="a" dimension="none" value="0"/>
<Constant name="b" dimension="none" value="0"/>
<Constant name="c" dimension="none" value="0"/>
<Constant name="d" dimension="none" value="0"/>
<Dynamics>
<DerivedVariable name="V" dimension="none" value="v / VOLT_SCALE"/>
<ConditionalDerivedVariable name="t" exposure="t" dimension="time">
<Case condition="(V + fastNa_shift) .lt. ( -30 )" value="( 0.025 + 0.14 * ( exp ( ((V + fastNa_shift) + 30) / 10) ) ) * TIME_SCALE"/>
<Case value="( 0.02 + a + (0.145 + b) * ( exp ( -1 * ((V + fastNa_shift + d) + 30) / (10.0 + c)) )) * TIME_SCALE"/>
</ConditionalDerivedVariable>
</Dynamics>
</ComponentType>
<ComponentType name="naf_m_inf_inf" extends="baseVoltageDepVariable">
<Constant name="TIME_SCALE" dimension="time" value="1 ms"/>
<Constant name="VOLT_SCALE" dimension="voltage" value="1 mV"/>
<Constant name="fastNa_shift" dimension="none" value="0"/>
<Constant name="a" dimension="none" value="0"/>
<Constant name="b" dimension="none" value="0"/>
<Constant name="c" dimension="none" value="0"/>
<Constant name="d" dimension="none" value="0"/>
<Dynamics>
<DerivedVariable name="V" dimension="none" value="v / VOLT_SCALE"/>
<DerivedVariable name="x" exposure="x" dimension="none" value=" 1 / ( 1 + (exp ( ( -1 * (V + fastNa_shift) - 38) / 10)) ) "/>
</Dynamics>
</ComponentType>
<ComponentType name="naf_h_tau_tau" extends="baseVoltageDepTime">
<Constant name="TIME_SCALE" dimension="time" value="1 ms"/>
<Constant name="VOLT_SCALE" dimension="voltage" value="1 mV"/>
<Constant name="fastNa_shift" dimension="none" value="0"/>
<Constant name="a" dimension="none" value="0"/>
<Constant name="b" dimension="none" value="0"/>
<Constant name="c" dimension="none" value="0"/>
<Constant name="d" dimension="none" value="0"/>
<Dynamics>
<DerivedVariable name="V" dimension="none" value="v / VOLT_SCALE"/>
<DerivedVariable name="t" exposure="t" dimension="time" value="(0.15 + 1.15 / ( 1 + ( exp (( ( V + fastNa_shift * 0 ) + 37 ) / 15) ) )) * TIME_SCALE"/>
</Dynamics>
</ComponentType>
<ComponentType name="naf_h_inf_inf" extends="baseVoltageDepVariable">
<Constant name="TIME_SCALE" dimension="time" value="1 ms"/>
<Constant name="VOLT_SCALE" dimension="voltage" value="1 mV"/>
<Constant name="fastNa_shift" dimension="none" value="0"/>
<Constant name="a" dimension="none" value="0"/>
<Constant name="b" dimension="none" value="0"/>
<Constant name="c" dimension="none" value="0"/>
<Constant name="d" dimension="none" value="0"/>
<Dynamics>
<DerivedVariable name="V" dimension="none" value="v / VOLT_SCALE"/>
<DerivedVariable name="x" exposure="x" dimension="none" value="1 / ( 1 + (exp (( ( V + fastNa_shift * 0 ) + 62.9 ) / 10.7)) )"/>
</Dynamics>
</ComponentType>
<notes>ChannelML file based on Traub et al. 2003</notes>
<ionChannel id="naf2" conductance="10pS" type="ionChannelHH" species="na">
<notes>Fast Sodium transient (inactivating) current. Channel used in Traub et al 2005, slight modification of naf from Traub et al 2003</notes>
<annotation>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
<rdf:Description rdf:about="naf2">
<bqmodel:isDescribedBy xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
<rdf:Bag>
<rdf:li>Roger D. Traub, Eberhard H. Buhl, Tengis Gloveli, and Miles A. Whittington
Fast Rhythmic Bursting Can Be Induced in Layer 2/3 Cortical Neurons by Enhancing Persistent Na+ Conductance or by Blocking BK Channels
J Neurophysiol 89: 909-921, 2003</rdf:li>
<rdf:li rdf:resource="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=pubmed&amp;dopt=Abstract&amp;list_uids=12574468"/>
</rdf:Bag>
</bqmodel:isDescribedBy>
<bqmodel:isDescribedBy xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
<rdf:Bag>
<rdf:li>Roger D. Traub, Diego Contreras, Mark O. Cunningham, Hilary Murray, Fiona E. N. LeBeau, Anita Roopun, Andrea Bibbig, W. Bryan Wilent, Michael J. Higley, and Miles A. Whittington
Single-column thalamocortical network model exhibiting gamma oscillations, sleep spindles, and epileptogenic bursts.
J. Neurophysiol. 93, 2194-2232, 2005</rdf:li>
<rdf:li rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/15525801?dopt=Abstract"/>
</rdf:Bag>
</bqmodel:isDescribedBy>
<bqbiol:isVersionOf xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
<rdf:Bag>
<rdf:li>Na channels</rdf:li>
<rdf:li rdf:resource="http://senselab.med.yale.edu/senselab/NeuronDB/channelGene2.htm#table2"/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<gate id="m" type="gateHHtauInf" instances="3">
<timeCourse type="naf2_m_tau_tau"/>
<steadyState type="naf2_m_inf_inf"/>
</gate>
<gate id="h" type="gateHHtauInf" instances="1">
<timeCourse type="naf2_h_tau_tau"/>
<steadyState type="naf2_h_inf_inf"/>
</gate>
</ionChannel>
<ComponentType name="naf2_m_tau_tau" extends="baseVoltageDepTime">
<Constant name="TIME_SCALE" dimension="time" value="1 ms"/>
<Constant name="VOLT_SCALE" dimension="voltage" value="1 mV"/>
<Constant name="fastNa_shift" dimension="none" value="0"/>
<Constant name="a" dimension="none" value="0"/>
<Constant name="b" dimension="none" value="0"/>
<Constant name="c" dimension="none" value="0"/>
<Constant name="d" dimension="none" value="0"/>
<Dynamics>
<DerivedVariable name="V" dimension="none" value="v / VOLT_SCALE"/>
<ConditionalDerivedVariable name="t" exposure="t" dimension="time">
<Case condition="( V + fastNa_shift ) .lt. ( -30 )" value="( 0.0125 + 0.1525 * ( exp ( ((V + fastNa_shift) + 30) / 10) ) ) * TIME_SCALE"/>
<Case value="( 0.02 + a + (0.145 + b) * ( exp ( -1 * ((V + fastNa_shift + d) + 30) / (10 + c)) )) * TIME_SCALE"/>
</ConditionalDerivedVariable>
</Dynamics>
</ComponentType>
<ComponentType name="naf2_m_inf_inf" extends="baseVoltageDepVariable">
<Constant name="TIME_SCALE" dimension="time" value="1 ms"/>
<Constant name="VOLT_SCALE" dimension="voltage" value="1 mV"/>
<Constant name="fastNa_shift" dimension="none" value="0"/>
<Constant name="a" dimension="none" value="0"/>
<Constant name="b" dimension="none" value="0"/>
<Constant name="c" dimension="none" value="0"/>
<Constant name="d" dimension="none" value="0"/>
<Dynamics>
<DerivedVariable name="V" dimension="none" value="v / VOLT_SCALE"/>
<DerivedVariable name="x" exposure="x" dimension="none" value=" 1 / ( 1 + (exp ( ( -1 * (V + fastNa_shift) - 38) / 10)) ) "/>
</Dynamics>
</ComponentType>
<ComponentType name="naf2_h_tau_tau" extends="baseVoltageDepTime">
<Constant name="TIME_SCALE" dimension="time" value="1 ms"/>
<Constant name="VOLT_SCALE" dimension="voltage" value="1 mV"/>
<Constant name="fastNa_shift" dimension="none" value="0"/>
<Constant name="a" dimension="none" value="0"/>
<Constant name="b" dimension="none" value="0"/>
<Constant name="c" dimension="none" value="0"/>
<Constant name="d" dimension="none" value="0"/>
<Dynamics>
<DerivedVariable name="V" dimension="none" value="v / VOLT_SCALE"/>
<DerivedVariable name="t" exposure="t" dimension="time" value="(0.225 + 1.125 / ( 1 + ( exp (( ( V + fastNa_shift * 0 ) + 37 ) / 15) ) )) * TIME_SCALE"/>
</Dynamics>
</ComponentType>
<ComponentType name="naf2_h_inf_inf" extends="baseVoltageDepVariable">
<Constant name="TIME_SCALE" dimension="time" value="1 ms"/>
<Constant name="VOLT_SCALE" dimension="voltage" value="1 mV"/>
<Constant name="fastNa_shift" dimension="none" value="0"/>
<Constant name="a" dimension="none" value="0"/>
<Constant name="b" dimension="none" value="0"/>
<Constant name="c" dimension="none" value="0"/>
<Constant name="d" dimension="none" value="0"/>
<Dynamics>
<DerivedVariable name="V" dimension="none" value="v / VOLT_SCALE"/>
<DerivedVariable name="x" exposure="x" dimension="none" value="1 / ( 1 + (exp (( ( V + fastNa_shift * 0 ) + 58.3 ) / 6.7)) )"/>
</Dynamics>
</ComponentType>
<notes>ChannelML file based on Traub et al. 2003</notes>
<ionChannel id="naf2__a0__b0__c0__d0__fastNa_shiftmin2_5" conductance="10pS" type="ionChannelHH" species="na">
<notes>Fast Sodium transient (inactivating) current. Channel used in Traub et al 2005, slight modification of naf from Traub et al 2003</notes>
<annotation>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
<rdf:Description rdf:about="naf2">
<bqmodel:isDescribedBy xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
<rdf:Bag>
<rdf:li>Roger D. Traub, Eberhard H. Buhl, Tengis Gloveli, and Miles A. Whittington
Fast Rhythmic Bursting Can Be Induced in Layer 2/3 Cortical Neurons by Enhancing Persistent Na+ Conductance or by Blocking BK Channels
J Neurophysiol 89: 909-921, 2003</rdf:li>
<rdf:li rdf:resource="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=pubmed&amp;dopt=Abstract&amp;list_uids=12574468"/>
</rdf:Bag>
</bqmodel:isDescribedBy>
<bqmodel:isDescribedBy xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
<rdf:Bag>
<rdf:li>Roger D. Traub, Diego Contreras, Mark O. Cunningham, Hilary Murray, Fiona E. N. LeBeau, Anita Roopun, Andrea Bibbig, W. Bryan Wilent, Michael J. Higley, and Miles A. Whittington
Single-column thalamocortical network model exhibiting gamma oscillations, sleep spindles, and epileptogenic bursts.
J. Neurophysiol. 93, 2194-2232, 2005</rdf:li>
<rdf:li rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/15525801?dopt=Abstract"/>
</rdf:Bag>
</bqmodel:isDescribedBy>
<bqbiol:isVersionOf xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
<rdf:Bag>
<rdf:li>Na channels</rdf:li>
<rdf:li rdf:resource="http://senselab.med.yale.edu/senselab/NeuronDB/channelGene2.htm#table2"/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<gate id="m" type="gateHHtauInf" instances="3">
<timeCourse type="naf2__a0__b0__c0__d0__fastNa_shiftmin2_5__a0__b0__c0__d0__fastNa_shiftmin2_5__a0__b0__c0__d0__fastNa_shiftmin2_5__a0__b0__c0__d0__fastNa_shiftmin2_5__a0__b0__c0__d0__fastNa_shiftmin2_5_m_tau_tau"/>
<steadyState type="naf2__a0__b0__c0__d0__fastNa_shiftmin2_5__a0__b0__c0__d0__fastNa_shiftmin2_5__a0__b0__c0__d0__fastNa_shiftmin2_5__a0__b0__c0__d0__fastNa_shiftmin2_5__a0__b0__c0__d0__fastNa_shiftmin2_5_m_inf_inf"/>
</gate>
<gate id="h" type="gateHHtauInf" instances="1">
<timeCourse type="naf2__a0__b0__c0__d0__fastNa_shiftmin2_5__a0__b0__c0__d0__fastNa_shiftmin2_5__a0__b0__c0__d0__fastNa_shiftmin2_5__a0__b0__c0__d0__fastNa_shiftmin2_5__a0__b0__c0__d0__fastNa_shiftmin2_5_h_tau_tau"/>
<steadyState type="naf2__a0__b0__c0__d0__fastNa_shiftmin2_5__a0__b0__c0__d0__fastNa_shiftmin2_5__a0__b0__c0__d0__fastNa_shiftmin2_5__a0__b0__c0__d0__fastNa_shiftmin2_5__a0__b0__c0__d0__fastNa_shiftmin2_5_h_inf_inf"/>
</gate>
</ionChannel>
<ComponentType name="naf2__a0__b0__c0__d0__fastNa_shiftmin2_5__a0__b0__c0__d0__fastNa_shiftmin2_5__a0__b0__c0__d0__fastNa_shiftmin2_5__a0__b0__c0__d0__fastNa_shiftmin2_5__a0__b0__c0__d0__fastNa_shiftmin2_5_m_tau_tau" extends="baseVoltageDepTime">
<Constant name="TIME_SCALE" dimension="time" value="1 ms"/>
<Constant name="VOLT_SCALE" dimension="voltage" value="1 mV"/>
<Constant name="fastNa_shift" dimension="none" value="-2.5"/>
<Constant name="a" dimension="none" value="0.0"/>
<Constant name="b" dimension="none" value="0.0"/>
<Constant name="c" dimension="none" value="0.0"/>
<Constant name="d" dimension="none" value="0.0"/>
<Dynamics>
<DerivedVariable name="V" dimension="none" value="v / VOLT_SCALE"/>
<ConditionalDerivedVariable name="t" exposure="t" dimension="time">
<Case condition="( V + fastNa_shift ) .lt. ( -30 )" value="( 0.0125 + 0.1525 * ( exp ( ((V + fastNa_shift) + 30) / 10) ) ) * TIME_SCALE"/>
<Case value="( 0.02 + a + (0.145 + b) * ( exp ( -1 * ((V + fastNa_shift + d) + 30) / (10 + c)) )) * TIME_SCALE"/>
</ConditionalDerivedVariable>
</Dynamics>
</ComponentType>
<ComponentType name="naf2__a0__b0__c0__d0__fastNa_shiftmin2_5__a0__b0__c0__d0__fastNa_shiftmin2_5__a0__b0__c0__d0__fastNa_shiftmin2_5__a0__b0__c0__d0__fastNa_shiftmin2_5__a0__b0__c0__d0__fastNa_shiftmin2_5_m_inf_inf" extends="baseVoltageDepVariable">
<Constant name="TIME_SCALE" dimension="time" value="1 ms"/>
<Constant name="VOLT_SCALE" dimension="voltage" value="1 mV"/>
<Constant name="fastNa_shift" dimension="none" value="-2.5"/>
<Constant name="a" dimension="none" value="0.0"/>
<Constant name="b" dimension="none" value="0.0"/>
<Constant name="c" dimension="none" value="0.0"/>
<Constant name="d" dimension="none" value="0.0"/>
<Dynamics>
<DerivedVariable name="V" dimension="none" value="v / VOLT_SCALE"/>
<DerivedVariable name="x" exposure="x" dimension="none" value=" 1 / ( 1 + (exp ( ( -1 * (V + fastNa_shift) - 38) / 10)) ) "/>
</Dynamics>
</ComponentType>
<ComponentType name="naf2__a0__b0__c0__d0__fastNa_shiftmin2_5__a0__b0__c0__d0__fastNa_shiftmin2_5__a0__b0__c0__d0__fastNa_shiftmin2_5__a0__b0__c0__d0__fastNa_shiftmin2_5__a0__b0__c0__d0__fastNa_shiftmin2_5_h_tau_tau" extends="baseVoltageDepTime">
<Constant name="TIME_SCALE" dimension="time" value="1 ms"/>
<Constant name="VOLT_SCALE" dimension="voltage" value="1 mV"/>
<Constant name="fastNa_shift" dimension="none" value="-2.5"/>
<Constant name="a" dimension="none" value="0.0"/>
<Constant name="b" dimension="none" value="0.0"/>
<Constant name="c" dimension="none" value="0.0"/>
<Constant name="d" dimension="none" value="0.0"/>
<Dynamics>
<DerivedVariable name="V" dimension="none" value="v / VOLT_SCALE"/>
<DerivedVariable name="t" exposure="t" dimension="time" value="(0.225 + 1.125 / ( 1 + ( exp (( ( V + fastNa_shift * 0 ) + 37 ) / 15) ) )) * TIME_SCALE"/>
</Dynamics>
</ComponentType>
<ComponentType name="naf2__a0__b0__c0__d0__fastNa_shiftmin2_5__a0__b0__c0__d0__fastNa_shiftmin2_5__a0__b0__c0__d0__fastNa_shiftmin2_5__a0__b0__c0__d0__fastNa_shiftmin2_5__a0__b0__c0__d0__fastNa_shiftmin2_5_h_inf_inf" extends="baseVoltageDepVariable">
<Constant name="TIME_SCALE" dimension="time" value="1 ms"/>
<Constant name="VOLT_SCALE" dimension="voltage" value="1 mV"/>
<Constant name="fastNa_shift" dimension="none" value="-2.5"/>
<Constant name="a" dimension="none" value="0.0"/>
<Constant name="b" dimension="none" value="0.0"/>
<Constant name="c" dimension="none" value="0.0"/>
<Constant name="d" dimension="none" value="0.0"/>
<Dynamics>
<DerivedVariable name="V" dimension="none" value="v / VOLT_SCALE"/>
<DerivedVariable name="x" exposure="x" dimension="none" value="1 / ( 1 + (exp (( ( V + fastNa_shift * 0 ) + 58.3 ) / 6.7)) )"/>
</Dynamics>
</ComponentType>
<notes>ChannelML file based on Traub et al. 2003</notes>
<fixedFactorConcentrationModelTraub id="cad__beta0_02__phi260000" restingConc="0mol_per_cm3" beta="0.02 per_ms" ion="ca" phi="260000.0 mol_per_cm_per_uA_per_ms"/>
<notes>ChannelML file based on Traub et al. 2003</notes>
<fixedFactorConcentrationModelTraub id="cad__beta0_05__phi520000" restingConc="0mol_per_cm3" beta="0.05 per_ms" ion="ca" phi="520000.0 mol_per_cm_per_uA_per_ms"/>
<cell id="SupAxAx">
<notes>Cell: supaxax_0 exported from NEURON ModelView</notes>
<morphology id="morphology_SupAxAx">
<segment id="0" name="Seg0_comp_1">
<proximal x="0.0" y="0.0" z="0.0" diameter="15.0"/>
<distal x="0.0" y="10.0" z="0.0" diameter="15.0"/>
</segment>
<segment id="1" name="Seg1_comp_1">
<parent segment="0"/>
<distal x="-4.371139E-7" y="20.0" z="0.0" diameter="15.0"/>
</segment>
<segment id="106" name="Seg0_comp_54">
<parent segment="0" fractionAlong="0.0"/>
<proximal x="4.371139E-7" y="0.0" z="0.0" diameter="1.4"/>
<distal x="-3.7745E-7" y="-25.0" z="0.0" diameter="1.4"/>
</segment>
<segment id="107" name="Seg1_comp_54">
<parent segment="106"/>
<distal x="-1.1920139E-6" y="-50.0" z="0.0" diameter="1.4"/>
</segment>
<segment id="80" name="Seg0_comp_41">
<parent segment="1"/>
<proximal x="0.0" y="20.0" z="0.0" diameter="2.12"/>
<distal x="-16.0" y="8.0" z="0.0" diameter="2.12"/>
</segment>
<segment id="81" name="Seg1_comp_41">
<parent segment="80"/>
<distal x="-32.0" y="-4.0" z="0.0" diameter="2.12"/>
</segment>
<segment id="54" name="Seg0_comp_28">
<parent segment="1"/>
<proximal x="0.0" y="20.0" z="0.0" diameter="2.12"/>
<distal x="16.0" y="8.0" z="0.0" diameter="2.12"/>
</segment>
<segment id="55" name="Seg1_comp_28">
<parent segment="54"/>
<distal x="32.0" y="-4.0" z="0.0" diameter="2.12"/>
</segment>
<segment id="28" name="Seg0_comp_15">
<parent segment="1"/>
<proximal x="0.0" y="20.0" z="0.0" diameter="2.12"/>
<distal x="0.0" y="32.0" z="-16.0" diameter="2.12"/>
</segment>
<segment id="29" name="Seg1_comp_15">
<parent segment="28"/>
<distal x="0.0" y="44.0" z="-32.0" diameter="2.12"/>
</segment>
<segment id="2" name="Seg0_comp_2">
<parent segment="1"/>
<proximal x="0.0" y="20.0" z="0.0" diameter="2.12"/>
<distal x="0.0" y="32.0" z="16.0" diameter="2.12"/>
</segment>
<segment id="3" name="Seg1_comp_2">
<parent segment="2"/>
<distal x="0.0" y="44.0" z="32.0" diameter="2.12"/>
</segment>
<segment id="108" name="Seg0_comp_55">
<parent segment="107"/>
<proximal x="-1.1920139E-6" y="-50.0" z="0.0" diameter="1.2"/>
<distal x="-3.9139263E-6" y="-75.0" z="0.0" diameter="1.2"/>
</segment>
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</cell>
<cell id="SupBasket">
<notes>Cell: supbask_0 exported from NEURON ModelView</notes>
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<cell id="SupLTSInter">
<notes>Cell: supLTS_0 exported from NEURON ModelView</notes>
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