Hugo Schmitt hugows

brain

"In humans, both acute and chronic increases in ketone body availability to the central nervous system cause massive changes in cerebral fuel metabolism. In healthy middle-aged subjects, an i.v. infusion of BHB caused approximately 14% decrease in cerebral glucose consumption while oxygen use was unchanged, suggesting that ketone bodies, even when supplied acutely, enter the brain and may be utilized immediately as an alternative fuel to glucose. Similar cerebral metabolic changes have also been demonstrated in young individuals, however, at lower infusion rates, and thus lower BHB concentrations, glucose uptake does not seem to be affected. Together, this suggests an acute cerebral glucose-sparing effect when ketone availability is high." - "Effects of Ketone Bodies on Brain Metabolism and Function in Neurodegenerative Diseases" (2020)
"Recent evidence suggests that myelin lipids may act as glial energy reserves when glucose is lacking,

RFC Architecture + Database Schema modeling Challenge

How would you design Credit on top of Pix?

deliverables: markdown + excalidraw (your RFC proposal)

check this https://developers.celcoin.com.br/docs/plataforma-de-cr%C3%A9dito

Read this to understand https://blog.pragmaticengineer.com/scaling-engineering-teams-via-writing-things-down-rfcs/

Comments

A delicate matter, requiring taste and judgement. I tend to err on the side of eliminating comments, for several reasons. First, if the code is clear, and uses good type names and variable names, it should explain itself. Second, comments aren't checked by the compiler, so there is no guarantee they're right, especially after the code is modified. A misleading comment can be very confusing. Third, the issue of typography: comments clutter code.

Rob Pike, "Notes on Programming in C"

Minimal D3D11

Minimal D3D11 reference implementation: An uncluttered Direct3D 11 setup + basic rendering primer and API familiarizer. Complete, runnable Windows application contained in a single function and laid out in a linear, step-by-step fashion that should be easy to follow from the code alone. ~200 LOC. No modern C++, OOP or (other) obscuring cruft. View on YouTube

Also check out Minimal D3D11 pt2, reconfigured for instanced rendering and with a smaller, tighter, simplified overall code structure, or Minimal D3D11 pt3, with shadowmapping + showcasing a range of alternative setup and rendering techniques.

Swift Concurrency Manifesto

Author: Chris Lattner

Chinese Translation by Jason Yu

For a while, I thought that our modern culture's relationship to science best resembled the Catholic Church during the middle ages. Priests delivering sermons in Latin, indulgences, poor families of believers praying one of their sons would be bright enough for the clergy... Then I discovered the Druze.

"But when I asked him about the Druze faith, he gave me an unexpected reply. 'I know nothing about the Druze', the pre-eminent leader of the Druze declared with a violent wave of his arm. From his piles of books he selected a couple by Tariq Ali and gave them to me as gifts. He invited me to visit him at his palace in the mountains. And then he said goodbye. Either the most powerful Druze man in Lebanon, an intellectual in his own right, had been excluded from the teachings of his own religion, or else he knew better than to pass them on to an outsider. I had every intention of taking up his invitation to spend time among the Druze communities, but first I would have to find someone more willing to talk

	{
	"title": "Raycast Karabiner Config",
	"rules": [
	{
	"description": "Double click cmd Toggle Raycast(Hotkey: ctrl+option+cmd+Esc)",
	"manipulators": [
	{
	"conditions": [
	{
	"name": "command_pressed",

	knu = require("knu") -- https://github.com/knu/hs-knu

	-- Switch between Karabiner-Elements profiles as Barrier enters a different host
	do
	-- Configure Barrier (https://github.com/debauchee/barrier) to output log to ~/Library/Logs/barrier.log
	local logFile = os.getenv("HOME") .. "/Library/Logs/barrier.log"
	local lineNo = 1
	local host = nil
	local defaultProfile = "Default"
	local profileForHost = function (host)

	function MyResponsiveComponent() {
	const width = useWindowWidth(); // Our custom Hook
	return (
	<p>Window width is {width}</p>
	);
	}

	import React, { Component } from 'react';
	import ReactDOM from 'react-dom';
	import './index.css';
	import registerServiceWorker from './registerServiceWorker';

	class Dynamic extends Component {
	constructor(props) {
	super(props);
	this.state = { module: null };
	}